Suzetrigine for Pain Management After Tonsillectomy

(STOP Trial)

Age: 18+
Sex: Any
Trial Phase: Phase 4
Sponsor: Stanford University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this clinical trial is to learn if a non-opioid pain medicine called suzetrigine can lower how much opioid pain medicine adults need after tonsil surgery (tonsillectomy) or a similar throat surgery.

Who Is on the Research Team?

TT

Tristan Tham, MD

Principal Investigator

Stanford University

Are You a Good Fit for This Trial?

This trial is for adults who are having their tonsils removed or a similar throat surgery and need pain management afterward. People with certain medical conditions, allergies to study drugs, or other factors that could affect safety may not be able to join.

Inclusion Criteria

I am scheduled for a tonsil or throat surgery as part of this study.
Able to understand the consent discussion in English by telephone, provide informed consent, and comply with study procedures including completion of electronic patient-reported outcome surveys
I am able and willing to do daily pain surveys and track my opioid use for 14 days.

Exclusion Criteria

Chronic opioid use
Pregnant or breastfeeding
I am unable to fill out questionnaires because of language, reading, or health issues.
See 4 more

What Are the Treatments Tested in This Trial?

Interventions

  • Suzetrigine

Trial Overview

The study tests whether suzetrigine, a non-opioid pain medicine, can reduce the amount of opioid (oxycodone) needed after tonsil or throat surgery. Acetaminophen is also used as part of standard care.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Suzetrigine (100-50mg)Experimental Treatment3 Interventions
Group II: Standard of careActive Control2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Stanford University

Lead Sponsor

Trials
2,527
Recruited
17,430,000+