30 Participants Needed

Cetaphil for Crepey Skin

Recruiting at 1 trial location
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a skincare product, Cetaphil, to determine its effectiveness on crepey skin, which is thin, fragile, and crinkly, often due to sun damage. Participants will apply the product to areas like the knees and hands, and researchers will assess changes in skin texture and firmness over 12 weeks. Individuals with mild-to-moderate crepey skin who are open to switching their current skincare routine to this product may be suitable candidates. The trial seeks a diverse group of adults who notice their skin bruises easily and are in generally good health. As a Phase 4 trial, this study aims to understand how the already FDA-approved and effective treatment benefits more patients.

Will I have to stop taking my current medications?

You will need to stop using your current topical skincare products and replace them with the study product for the duration of the trial. The protocol does not specify stopping other medications, but you must refrain from using certain products and medications that could affect the study results.

What is the safety track record for this treatment?

Research shows that most people can use Cetaphil products without problems. Cetaphil Skin Activator Hydrating & Firming Cream is designed to be gentle. It is hypoallergenic, meaning it is unlikely to cause allergic reactions, and it does not contain fragrances or parabens, reducing the likelihood of irritating sensitive skin.

However, individuals with very sensitive skin might still experience irritation. Those with sensitive skin should exercise caution when trying new products. Overall, Cetaphil products are considered safe, and many people use them without issues.12345

Why are researchers enthusiastic about this study treatment?

Cetaphil is unique because it offers a gentle, accessible option for addressing crepey skin, which is often treated with more aggressive methods like retinoids or laser therapy. Cetaphil stands out due to its moisturizing properties that help improve skin elasticity and texture without the irritation that can accompany stronger treatments. Researchers are excited about Cetaphil because it provides a simpler, over-the-counter alternative that could make a difference in skin appearance with regular application.

What is the effectiveness track record for Cetaphil in treating crepey skin?

Research has shown that Cetaphil's Skin Activator Hydrating & Firming Cream effectively reduces crepey skin. One study found that 88% of users noticed smoother skin in just two days, and 94% saw firmer skin after one month. This product contains a small amount of AHA, a gentle acid that renews skin cells, reducing dullness and unevenness. Overall, this cream has shown promising results in improving skin texture and firmness. Participants in this trial will apply topical skincare products, including Cetaphil, to the body to further evaluate its effectiveness.36789

Are You a Good Fit for This Trial?

Adults aged 40-60 with mild-to-moderate crepey skin, wrinkles, and signs of aging due to sun exposure can join this study. Participants must be in good health and willing to switch their skincare routine exclusively to the trial's product for its duration. All skin types are welcome, but there's a special effort to include diverse racial and ethnic groups.

Inclusion Criteria

I am between 40 and 60 years old.
I am of any ethnicity, with efforts to include Hispanic, Latino, or Spanish origin.
I have a history of easily bruised or fragile skin.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants apply a topical skincare regimen to the knees, thighs, hands, and all over the body

12 weeks
Evaluations at 4 weeks, 8 weeks, and 12 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Cetaphil

Trial Overview

The trial is testing the effectiveness of Cetaphil as a topical treatment for improving the appearance of mature, crepey skin on various body parts over 12 weeks. Participants will apply it regularly and undergo assessments at different stages to measure changes.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Skincare Product TreatmentExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Galderma R&D

Lead Sponsor

Trials
303
Recruited
60,700+
Flemming Ørnskov profile image

Flemming Ørnskov

Galderma R&D

Chief Executive Officer since 2019

MD, MPH

Baldo Scassellati Sforzolini profile image

Baldo Scassellati Sforzolini

Galderma R&D

Chief Medical Officer

MD, PhD

Citations

A Clinical Study to Assess Efficacy and Tolerability of a ...

Subjects will apply Cetaphil Hydrating and Firming Cream Skin Activator to the knees, thighs, hands, and all of the body at least twice daily.

Galderma launches transformative skincare segment with ...

In clinical trials, the Skin Activator Hydrating & Firming Lotion showed to be effective in improving the appearance of skin crepiness and ...

Skin Activator Hydrating & Firming collection

Microdosed AHA (Mandelic Acid) helps increase surface skin cell turnover to visibly reduce dull, uneven skin.

Skin Activator Hydrating & Firming Cream

88% said skin looked less crepey in 2 days and 94% said skin looked firmer after just 1 month. Cetaphil firming skin cream is hypoallergenic, fragrance free, ...

Launching Cetaphil's Hydrating & Firming Cream to HCPs

Cetaphil introduced a groundbreaking new product, SKIN ACTIVATOR Hydrating & Firming Cream, designed to address crepey skin with a proprietary blend of ...

SAFETY DATA SHEET

SKIN: May be irritating to the skin in some sensitive individuals. EYES: Moderate irritation may occur. INHALTION: This product is nonvolatile; therefore, ...

Cetaphil Cracked Skin Repair Lotion Rating

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, ...

Cetaphil Skin Activator Hydrating & Firming Body Cream ...

Users saw results even sooner as 88% noted less crepey skin in just 2 days and 94% noted visibly firmer skin in 1 week. How does CETAPHIL Skin Activator ...

Cetaphil Hydrating & Firming Lotion, 16 fl oz/473 mL

Ingredients reviewed for Cetaphil Hydrating & Firming Lotion to be 91% Top Allergen Free and free of Gluten, Nickel, Preservatives, Lanolin, Talc, ...