Lurasidone for Bipolar Disorder
What You Need to Know Before You Apply
What is the purpose of this trial?
People with a diagnosis of bipolar disorder who are depressed will have a light-based imaging of the brain (Near Infrared Spectroscopy) before and after they have treatment for their depression with a standard, approved medication named lurasidone. They will also answer questions about their history, and give blood samples. The goal is to understand the role of mitochondrial activity in bipolar disorder. Healthy volunteers who have never had a psychiatric disorder will have the same procedures, but they will not receive the medication.
Who Is on the Research Team?
Martin Lan, MD PhD
Principal Investigator
Research Foundation for Mental Hygiene, Inc.
Are You a Good Fit for This Trial?
This trial is for adults diagnosed with bipolar disorder who are currently experiencing depression. Healthy volunteers without any history of psychiatric disorders can also participate, but they will not receive the medication.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Lurasidone
Trial Overview
Researchers are using a brain imaging technique (Near Infrared Spectroscopy) to study changes before and after treatment with lurasidone, an approved medication for bipolar depression. Healthy volunteers undergo the same scans but do not take the drug.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participants in a major depressive episode will receive standard treatment with lurasidone for six weeks. Doses can be adjusted based on clinical need.
Healthy Volunteers will have all research procedures, but will not receive medication treatment
Find a Clinic Near You
Who Is Running the Clinical Trial?
Martin Lan
Lead Sponsor
National Institute of Mental Health (NIMH)
Collaborator
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.