376 Participants NeededMy employer runs this trial

Inhaled Mosliciguat for Pulmonary Hypertension

Recruiting at 2 trial locations
PI
Overseen ByPulmovant Inc
Age: 18+
Sex: Any
Trial Phase: Phase 3
Sponsor: Pulmovant, Inc.
Pivotal Trial (Near Approval)This treatment is in the last trial phase before FDA approval
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

A Phase 3, Multicenter, Randomized, Double-Blind Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Inhaled Mosliciguat in Participants with Pulmonary Hypertension Associated with Interstitial Lung Disease

Who Is on the Research Team?

UM

Ubaldo Martin

Principal Investigator

Pulmovant, Inc.

Are You a Good Fit for This Trial?

This trial is for adults with pulmonary hypertension caused by interstitial lung disease. Participants should have a confirmed diagnosis and stable condition. People with other serious heart or lung diseases, recent major health events, or certain medication use may not be eligible.

Inclusion Criteria

Participants willing and able to provide informed consent
Confirmed pulmonary hypertension by right heart catheterization (RHC)
I can walk at least 100 meters in six minutes.
See 2 more

Exclusion Criteria

I have not had any experimental treatments in the last 42 days.
I need more than 10 liters per minute of oxygen while resting.
I started or am in the early phase of lung rehab within the last 28 days.
See 3 more

What Are the Treatments Tested in This Trial?

Interventions

  • Mosliciguat

Trial Overview

The study tests an inhaled drug called Mosliciguat (delivered via dry powder inhaler) compared to a placebo. Participants are randomly assigned to either group, and neither they nor the researchers know which treatment they're getting.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: ExtensionExperimental Treatment2 Interventions
Group II: MosliciguatActive Control2 Interventions
Group III: Matched PlaceboPlacebo Group2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Pulmovant, Inc.

Lead Sponsor

Trials
1
Recruited
120+