Search > Measles
1209 Participants NeededMy employer runs this trial

Combined Measles, Mumps, Rubella and Varicella Vaccine for Children

Recruiting at 13 trial locations
Age: < 18
Sex: Any
Trial Phase: Phase 3
Sponsor: GlaxoSmithKline
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Pivotal Trial (Near Approval)This treatment is in the last trial phase before FDA approval
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This study is evaluating the immunogenicity and safety of intramuscular administration of the investigational MMRVNS vaccine compared to intramuscular administration of the MMRV (Merck's measles, mumps, rubella and varicella) vaccine (ProQuad) that is already licensed for this route, when administered as a second dose in children 15 months to 6 years of age who were previously primed with a first dose of any combination of measles, mumps, rubella and varicella-containing vaccine(s).

Are You a Good Fit for This Trial?

This trial is for healthy children aged 15 months to 6 years who have already received their first dose of measles, mumps, rubella, and chickenpox (varicella) vaccines. Parents or guardians must give consent, and the child should be able to follow study procedures.

Inclusion Criteria

I am healthy as confirmed by a recent medical exam.
I received my first MMR vaccine when I was 1 year old.
I have given my informed consent according to local laws.
See 7 more

What Are the Treatments Tested in This Trial?

Interventions

  • MMRV
  • MMRVNS

Trial Overview

The study compares a new combined vaccine (MMRVNS) with an approved vaccine (MMRV/ProQuad), both given as a second shot by muscle injection. The goal is to see how well each works and how safe they are in young children.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: MMRVNS GroupExperimental Treatment1 Intervention
Group II: MMRV GroupActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

GlaxoSmithKline

Lead Sponsor

Trials
4,834
Recruited
8,389,000+
Headquarters
London, UK
Known For
Vaccines & Medicines
Top Products
**Advair (salmeterol, fluticasone propionate)**, **Shingrix (shingles vaccine)**, **Augmentin (amoxicillin/clavulanate potassium)**, **Ventolin (salbutamol sulfate)
Dame Emma Walmsley profile image

Dame Emma Walmsley

GlaxoSmithKline

Chief Executive Officer since 2017

MA in Classics and Modern Languages from Oxford University

Dr. Hal Barron profile image

Dr. Hal Barron

GlaxoSmithKline

Chief Medical Officer since 2018

MD from Harvard Medical School

Unbiased Results

We believe in providing patients with all the options.

Your Data Stays Your Data

We only share your information with the clinical trials you're trying to access.

Verified Trials Only

All of our trials are run by licensed doctors, researchers, and healthcare companies.