20 Participants NeededMy employer runs this trial

Cold Temperature for Fat Oxidation During Exercise

CB
CC
Overseen ByChristina Cheng
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Colorado State University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether cold temperatures affect how men and women burn fat differently during exercise. Participants will cycle in a room set at either normal temperature or a chilly 5 ºC (about 41 ºF). The study seeks individuals who exercise regularly (at least 150 minutes a week) and have not experienced significant weight changes recently. Those willing to avoid caffeine and alcohol before sessions may qualify. As an unphased trial, this study provides a unique opportunity to contribute to the scientific understanding of exercise and metabolism.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications. However, if you use hormonal contraceptives, you cannot participate.

What prior data suggests that exercising at cold temperatures is safe?

Research has shown that cold exposure can positively affect how the body uses energy. Studies have found that cold temperatures can help the body burn more fat and increase energy use. For instance, one study discovered that exercising in the cold enhances fat burning. Another study found that cold exposure boosts energy use and improves fat metabolism. Thus, in cold conditions, the body uses more energy and burns more fat.

Regarding safety, the studies reported no negative effects from cold exposure. Generally, cold exposure is safe for healthy individuals. This trial does not test a new drug or treatment with unknown side effects; it involves exercising in cold temperatures, a common practice. Prospective participants should consult a healthcare provider before joining the trial.12345

Why are researchers excited about this trial?

Researchers are excited about using cold temperatures during exercise because it might boost fat oxidation more effectively than exercising at room temperature. Most current methods to enhance fat burning during workouts focus on increasing intensity or duration. However, exercising in a cold environment could activate brown fat, which burns calories to generate heat, potentially leading to greater fat loss. This approach not only offers a novel mechanism beyond standard exercise and diet routines but also could be particularly beneficial for enhancing weight loss and improving metabolic health.

What evidence suggests that cold temperature is effective for fat oxidation during exercise?

Research has shown that exercising in cold weather can help burn more fat. One study found that cold exposure increases fat burning, meaning the body uses more fat for energy. Another study demonstrated that cold temperatures can boost energy use and activate a special type of fat that burns calories. Cold weather can also induce shivering to maintain warmth, which burns additional calories. In this trial, participants will exercise at either room temperature or in a cold environment to compare the effects on fat oxidation. Overall, exercising in the cold might enhance fat burning compared to warmer conditions.12367

Who Is on the Research Team?

CB

Christopher Bell

Principal Investigator

Colorado State University

Are You a Good Fit for This Trial?

This trial is for adults aged 18-40 who exercise regularly, have had stable weight for the past 6 months, and can communicate clearly in English. Participants must avoid caffeine and alcohol before visits.

Inclusion Criteria

Weight stable (no change in body mass greater than 5 lbs. within the previous 6 months)
Willing to abstain from caffeine and alcohol for 24-hours prior to two different study visits
Competency in English as informally assessed by comprehension of the Informed Consent. This study involves maximal exercise testing; for safety reasons, the ability for clear and rapid communication will be necessary between the research participants and the investigators
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Exclusion Criteria

Use of hormonal contraceptives
Pregnancy or breast feeding
Habitual use of tobacco/nicotine products or recreational drugs (2 or more uses within the previous month)
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants will ride an exercise bike at room temperature and cold temperature to measure maximal fat oxidation

1 week
2 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

2 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Cold temperature

Trial Overview

The study compares how exercising in cold versus room temperature affects fat burning differently in men and women. Each participant will do exercise tests under both conditions.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Exercise at cold temperatureExperimental Treatment1 Intervention
Group II: Exercise at room temperatureActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Colorado State University

Lead Sponsor

Trials
138
Recruited
38,200+

Citations

Cold exposure enhances fat utilization but not non-esterified ...

A rise in fat utilization in the cold was seen through lower respiratory quotient (RQ) (−0.03 ± 0.02), greater fat oxidation (+0.14 ± 0.13 g · ...

Effect of Acute Cold Exposure on Energy Metabolism and ...

Conclusion: Acute cold exposure could improve the energy expenditure and BAT activity in adults, which is beneficial for human against obesity. Keywords: ...

Environmental Temperature Affects Fat and Carbohydrate ...

The aim of the present study was to investigate the effects of temperature on fat oxidation in obese women during the recovery period after moderate intensity ...

Research Spotlight: Cold exposure for fat loss

The idea is that cold exposure will acutely increase sympathetic nervous system activity, shivering, and brown adipose tissue activation.

Exercise training and cold exposure trigger distinct ...

Exercise training and cold exposure both improve systemic metabolism, but the mechanisms are not well established.

Cold exposure stimulates cross-tissue metabolic rewiring ...

Cold exposure has profound effects on metabolism, including increased energy expenditure (1), enhanced lipolysis (2, 3) and improved insulin ...

A randomized trial of cold-exposure on energy expenditure ...

Healthy non-selected participants were randomized to achieve cold-exposure 1 hour/day, or to avoid any sense of feeling cold, for 6 weeks.