Mantram Repetition for PTSD
What You Need to Know Before You Apply
What is the purpose of this trial?
Approximately 450,000 Veterans Health Administration service users have both posttraumatic stress disorder (PTSD) and chronic pain (CP); treatments that efficiently target both PTSD and CP are limited, and new interventions should address the unique needs of Veterans with PTSD/CP. Mantram Repetition Program (MRP), a meditation-based program, appears well-suited to address these high-priority VA needs. MRP has established effectiveness for treatment of PTSD, is broadly acceptable, can be learned quickly and applied flexibly. However, rigorous testing is needed for pain-related outcomes among a PTSD/CP population. The proposed study will include a randomized controlled trial comparing the efficacy of MRP for PTSD/CP to Health Education while Living with Pain among a sample of 170 Veterans with comorbid PTSD/CP. The primary outcomes will be PTSD symptoms and pain interference. Results from this study will directly inform patient care among the nearly 4% of Veterans with PTSD/CP.
Who Is on the Research Team?
Anne L Malaktaris
Principal Investigator
VA San Diego Healthcare System, San Diego, CA
Are You a Good Fit for This Trial?
This trial is for U.S. veterans who have both PTSD and chronic, non-cancer pain that affects their daily life and has lasted at least 6 months. Participants must be able to join study activities. People with untreated severe substance use, serious mental illness, high suicide risk, or those already in similar therapies can't take part.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either the Mantram Repetition Program or Health Education in eight 90-minute group sessions delivered via telehealth
Follow-up
Participants are monitored for PTSD symptom severity and pain interference at multiple time points
What Are the Treatments Tested in This Trial?
Interventions
- Health Education while Living with Pain
- Mantram Repetition Program for PTSD + Pain
Trial Overview
The study compares two group programs: a meditation-based Mantram Repetition Program (MRP) designed to help with PTSD and pain, versus health education sessions about living with pain. Veterans are randomly assigned to one of the two groups.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
8-session group-based meditation training class led by a trained instructor
8-session group-based health education and discussion led by a trained instructor
Find a Clinic Near You
Who Is Running the Clinical Trial?
VA Office of Research and Development
Lead Sponsor
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