Mindful Walking for Dementia Risk
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether mindful walking can boost brain health and cognitive function, particularly for those at risk for Alzheimer's and related dementias (ADRD). Participants will either practice mindful walking, which combines walking with mindfulness techniques, or engage in regular walking. The goal is to determine if mindful walking offers additional benefits compared to walking alone. Suitable candidates for this trial are adults aged 60 or older who are sedentary, have a family history of dementia, notice cognitive issues, or are overweight. Participants must be able to walk independently and not anticipate major health changes in the next four months. As a Phase 2 trial, this research focuses on measuring the effectiveness of mindful walking in an initial, smaller group of people.
Do I need to stop my current medications for the trial?
The trial does not specify if you need to stop taking your current medications. It mentions that participants should be medically stable with or without medication, so it's likely you can continue your current meds.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research has shown that mindful walking is generally safe for older adults. This activity combines mindfulness and walking, both known for their safety. Studies have found that older adults handle mindful walking well, with no major problems reported. While researchers have mainly studied it for mental health benefits like reducing stress, new research suggests it might also help with thinking skills. Overall, mindful walking appears to be a low-risk option for those considering joining a clinical trial.12345
Why are researchers excited about this trial?
Researchers are excited about mindful walking for reducing dementia risk because it combines physical activity with mindfulness techniques, potentially offering cognitive benefits beyond standard exercise. Unlike traditional treatments for dementia prevention that focus primarily on physical exercise or medication, mindful walking incorporates mental awareness practices that may enhance brain health by reducing stress and improving mental clarity. This holistic approach is unique because it engages both the body and mind, aiming to create a more comprehensive effect on slowing cognitive decline.
What evidence suggests that mindful walking could be an effective treatment for dementia risk?
This trial will compare mindful walking with regular walking to assess their effects on dementia risk. Studies have shown that mindful walking may improve thinking skills in older adults. One study found that this type of walking can boost memory and attention. Another study suggested that it can strengthen parts of the brain affected by aging, potentially slowing memory loss. Walking in general is linked to a lower risk of dementia; specifically, people who walked about two miles a day were 25% less likely to develop it. While more research is needed, early findings suggest that mindful walking might be a promising way to support brain health in older adults.13467
Are You a Good Fit for This Trial?
This trial is for middle-aged and older adults in South Carolina who are at higher risk of developing Alzheimer's disease or related dementias. Participants should be able to walk and take part in supervised sessions, and must not have conditions that would prevent safe participation.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants engage in 8 sessions of mindful walking or walking-only control over 4 weeks
Follow-up
Participants are monitored for cognitive and neural function using fNIRS and other assessments
What Are the Treatments Tested in This Trial?
Interventions
- Mindfulness-based walking
Trial Overview
The study compares mindful walking (walking while practicing mindfulness techniques) with regular walking. Both groups attend eight supervised sessions over four weeks. Brain activity will be measured using a painless, non-invasive device called fNIRS.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Older adults will participate in 8 sessions of mindful walking over one month
Older adults will participate in 8 sessions of walking over one month
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of South Carolina
Lead Sponsor
USC Center for Clinical and Translational Research
Collaborator
USC The Center for Clinical & Translational Research
Collaborator
Citations
Implementation and evaluation of a community-based mindful ...
This paper documents the goal and protocol of a community-based, mindful walking randomized controlled trial to examine the short- and longer-term efficacy on ...
A Mindfulness-Based Lifestyle Intervention for Dementia ...
Our primary outcomes are feasibility, acceptability, appropriateness, credibility, satisfaction, and fidelity benchmarks. The secondary outcomes ...
3.
ctv.veeva.com
ctv.veeva.com/study/mindful-walking-neural-correlates-of-executive-function-in-sc-older-adults-at-risk-of-dementiasMindful Walking Neural Correlates of Executive Function in ...
However, most existing mindful walking studies have focused on mental health outcomes, such as stress reduction, rather than cognitive health.
Mindful walking and cognition in older adults: A proof of ...
This early-phase study (Phase IIa) provides preliminary support that mindful walking activity is promising for sustaining cognition in older adults.
5.
jbehavioralhealth.com
jbehavioralhealth.com/articles/Mindfulness-based%20walking%20vs%20%20seated%20meditation%20on%20anxiety%20%20affect%20%20fatigue%20%20and%20cognitionMindfulness-based walking vs. seated meditation on ...
Similarly, mindfulness-based walking was effective in enhancing cognition (p = 0.05); improving affective valence (p = 0.001) and excitement (p = 0.03); ...
Mindful Walking Neural Correlates of Executive Function in ...
Findings from this pilot study will provide important evidence on whether mindful walking can support brain and cognitive health in adults at ...
Mindfulness and Cognitive Training Interventions in Mild ...
Emerging research suggests that these approaches are feasible and safe in this population, with preliminary evidence of positive effects on aspects of cognition
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