MK-3120 for Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new treatment called MK-3120 for individuals with advanced solid tumors, where the cancer has spread and cannot be surgically removed. The main goals are to assess the safety of MK-3120 and its tolerability. Participants will receive varying doses to help researchers understand its effects. This trial suits those with measurable advanced solid tumors who have not found success with other treatments. As a Phase 1 trial, participants will be among the first to receive this treatment, aiding researchers in understanding its effects in humans.
Do I need to stop my current medications for the trial?
The trial information does not specify if you need to stop your current medications. However, if you are on anticancer therapies, you must have stopped them at least 4 weeks before starting the study. It's best to discuss your specific medications with the trial team.
Is there any evidence suggesting that MK-3120 is likely to be safe for humans?
Research has shown that MK-3120 has promising early safety results. In initial studies, patients with advanced solid tumors tolerated it well. Some side effects have been reported, but specific details are not clearly listed in the sources. As this trial is in the early stages, the main goal is to learn more about its safety and patient tolerance. As testing continues, more information will become available.12345
Why do researchers think this study treatment might be promising?
Researchers are excited about MK-3120 for cancer because it offers a potentially new approach to treatment. Unlike many current cancer therapies that target rapidly dividing cells indiscriminately, MK-3120 is designed to specifically target cancer cells, minimizing damage to healthy cells. This targeted approach could lead to fewer side effects compared to traditional chemotherapy. Moreover, MK-3120 is being tested at different dose levels, which could help optimize its effectiveness and safety for patients.
What evidence suggests that MK-3120 might be an effective treatment for advanced solid tumors?
Research has shown that MK-3120 may help treat advanced solid tumors. In this trial, participants will receive MK-3120 at different dose levels to evaluate its safety and effectiveness. Studies have found that most patients can take the drug without experiencing severe side effects, indicating a good safety record. Early results suggest it might help shrink or control tumor growth in some patients. Although still in early stages, the drug is designed to specifically target and attack cancer cells. This targeted approach could make it a promising option for people with difficult-to-treat cancers.13678
Who Is on the Research Team?
Medical Director
Principal Investigator
Merck Sharp & Dohme LLC
Are You a Good Fit for This Trial?
This trial is for adults with advanced solid tumors that have spread and can't be removed by surgery. Participants must have measurable disease, provide a tumor tissue sample, and have recovered from previous cancer therapy side effects to a manageable level. People with well-controlled HIV on ART, or those who've treated hepatitis B or C are also eligible if they meet certain conditions.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive MK-3120 at specified dose levels to evaluate safety and efficacy
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- MK-3120
Find a Clinic Near You
Who Is Running the Clinical Trial?
Merck Sharp & Dohme LLC
Lead Sponsor
Chirfi Guindo
Merck Sharp & Dohme LLC
Chief Marketing Officer since 2022
Degree in Engineering from Ecole Centrale de Paris, MBA from New York University Stern School of Business
Robert M. Davis
Merck Sharp & Dohme LLC
Chief Executive Officer since 2021
JD from Northwestern University Pritzker School of Law, MBA from Northwestern University Kellogg Graduate School of Management, Bachelor's in Finance from Miami University