Radiation for Spine Cancer

This trial explores whether a precise form of radiation, known as stereotactic body radiation therapy (SBRT), can treat spine cancer without major surgery. It targets individuals whose cancer has aggressively spread to the spine but who can still move around and have only minor muscle weakness. Participants must not have had any prior spine surgery or radiation for their condition. Those with certain types of cancer, such as small cell lung cancer, or an unstable spine are not eligible. The trial aims to find a less invasive treatment option that could improve quality of life. As a Phase 2 trial, the research focuses on measuring the treatment's effectiveness in an initial, smaller group of people.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Research has shown that stereotactic body radiation therapy (SBRT) for spine cancer is generally safe and well-tolerated. Studies indicate that it has a good safety record, allowing most patients to undergo treatment without major issues.

Many patients experience significant pain relief, and the treatment effectively controls the disease. Some reports mention that up to 35% of patients experienced complete relief from spinal pain three months after treatment.

Researchers are excited about SBRT (Stereotactic Body Radiation Therapy) for spine cancer because it offers a more precise and focused radiation treatment compared to traditional methods. Unlike standard radiation therapies, which can affect surrounding healthy tissues, SBRT delivers high doses of radiation directly to the tumor with pinpoint accuracy, minimizing damage to the spinal cord and other sensitive areas. This precision not only has the potential to improve outcomes by effectively targeting the cancer cells, but it also reduces the risk of side effects and shortens the overall treatment time, offering a more convenient and tolerable option for patients.

Research has shown that stereotactic body radiation therapy (SBRT), which participants in this trial will receive, works well for patients with metastatic spine cancer. Studies indicate that SBRT can stop cancer growth or shrink tumors in 80% to 96% of cases within one year. Additionally, SBRT has been found to reduce spinal pain for many patients. In one study, 35% of patients reported no spinal pain three months after receiving SBRT. Overall, SBRT offers a promising non-surgical treatment option for spine cancer.¹²³⁴⁶