BRX011 for Age-Related Macular Degeneration
(BELLAVISTA Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This study aims to evaluate the safety and efficacy of BRX011, an oral medication, taken once daily by participants with geographic atrophy secondary to age-related macular degeneration. The study is conducted in phases 1 and 2, focusing on assessing both safety (tolerability) and effectiveness (efficacy) of the treatment.
Participants: Adults with geographic atrophy due to age-related macular degeneration.
Treatment: BRX011 or Placebo is taken once daily as per the protocol.
Duration: The study involves multiple visits over 96 weeks to monitor participants' health and response to treatment.
Safety Monitoring: Regular checks for adverse events and health status to ensure participant well-being. Checks will include examination of vital signs, clinical labs, ocular exams, and ocular imaging.
Primary Outcome Measure: Efficacy of BRX011 in the annual rate of change in the square root of GA area, as specified in the protocol.
Are You a Good Fit for This Trial?
This trial is for adults aged 55 or older with geographic atrophy caused by age-related macular degeneration. Participants must have a certain level of vision, clear eye structures for exams, and be able to follow study procedures. Women must not be able to become pregnant.Inclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- BRX011
Trial Overview
The study tests BRX011, an oral medication taken once daily, compared to a placebo in people with geographic atrophy from macular degeneration. The goal is to see if BRX011 slows disease progression over about two years.
How Is the Trial Designed?
2
Treatment groups
Active Control
Placebo Group
Find a Clinic Near You
Who Is Running the Clinical Trial?
Biojiva LLC
Lead Sponsor
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.