A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The SKYLIGHT Trial)

Not yet recruiting at 11 trial locations
ST
Overseen BySKYLIGHT Trial Center
Age: 18+
Sex: Any
Trial Phase: Phase 2
Sponsor: Spyre Therapeutics, Inc.
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This Phase 2 study will test whether the investigational medicine, SPY072, improves hidradenitis suppurativa (HS) in adults with moderate to severe disease receiving advanced standard of care treatment. About 150 participants will be assigned by chance to receive either SPY072 or placebo for 16 weeks. Participants will be followed after the treatment period to evaluate safety and how long treatment effects may last.

Who Is on the Research Team?

JF

Joshua Friedman, MD, PhD

Principal Investigator

Spyre Therapeutics, Inc.

Are You a Good Fit for This Trial?

What Are the Treatments Tested in This Trial?

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: SPY072 + bimekizumabExperimental Treatment2 Interventions
Group II: Placebo + bimekizumabPlacebo Group2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Spyre Therapeutics, Inc.

Lead Sponsor

Trials
4
Recruited
270+