Cholestyramine for Environmental Exposures

SE
AM
Overseen ByAlina Merceron, MPH
Age: 18+
Sex: Any
Trial Phase: Phase 2
Sponsor: Emory University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this study is to evaluate whether treatment with cholestyramine for either one, two, three, or four months (up to 120 days), meaningfully influences per- and polyfluoroalkyl substances (PFAS) removal from the body.

Who Is on the Research Team?

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Stephanie Eick, PhD

Principal Investigator

Emory University

Are You a Good Fit for This Trial?

This trial is for people who have been exposed to PFAS chemicals in the environment and want to see if a treatment can help remove these substances from their bodies. Specific inclusion or exclusion criteria are not listed.

Inclusion Criteria

I mainly drink tap water.
Residence in the study area for at least 5 years
Not currently pregnant
See 4 more

Exclusion Criteria

I have digestive issues or take medicines that affect my gut.
I have taken antibiotics in the past three months.
I have had cancer before.
See 2 more

What Are the Treatments Tested in This Trial?

Interventions

  • Centrum
  • Cholestyramine

Trial Overview

The study tests whether taking cholestyramine, with Centrum vitamins, for up to four months helps reduce PFAS levels in the body. Participants may receive different lengths of treatment.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Cholestyramine therapy GroupExperimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Emory University

Lead Sponsor

Trials
1,735
Recruited
2,605,000+