VERVE-102 for High Cholesterol
(HEART-3 Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to measure the change in bad cholesterol (LDL-C) with VERVE-102 compared to placebo in adults who have plaque buildup in their arteries or are at high risk of developing it.
Who Is on the Research Team?
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 8 AM - 8 PM Eastern time (UTC/GMT - 5 hours, EST)
Principal Investigator
Eli Lilly and Company
Are You a Good Fit for This Trial?
This trial is for adults who have, or are at high risk for, heart and blood vessel diseases like high cholesterol, plaque buildup in arteries (atherosclerosis), heart attack, stroke, or coronary artery disease.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- VERVE-102
Trial Overview
The study compares a new drug called VERVE-102 to a placebo. Researchers want to see if VERVE-102 can lower bad cholesterol (LDL-C) in people with or at risk of cardiovascular problems.
How Is the Trial Designed?
4
Treatment groups
Experimental Treatment
Placebo Group
Participants will receive a single dose of VERVE-102 IV
Participants will receive a single dose of VERVE-102 IV
Participants will receive a single dose of VERVE-102 intravenously (IV)
Participants will receive a single dose of placebo IV
Find a Clinic Near You
Who Is Running the Clinical Trial?
Verve Therapeutics, Inc.
Lead Sponsor
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