PAAS Intervention for Adolescent Risky Behaviors

AT
AP
Overseen ByAdriana Pedroza, BA
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: University of California, Irvine
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a program called Pathways for African-Americans' Success (PAAS), which aims to reduce risky behaviors that might lead to HIV/AIDS and violence among African-American youth. Researchers seek to understand how this program affects brain regions linked to decision-making. Participants are divided into two groups: one receives the intervention immediately, while the other joins later. This trial suits African-American teens who can attend the six-week program with a parent or guardian and do not have major medical or behavioral issues. As an unphased trial, it offers participants a unique opportunity to contribute to important research that could positively impact their community.

Will I have to stop taking my current medications?

If you are on medications that affect the central nervous system, you may not be eligible to participate in the trial.

What prior data suggests that the PAAS intervention is safe for adolescents?

Research shows that the Pathways for African-Americans' Success (PAAS) program is safe for participants. Earlier studies found that PAAS improves parenting skills and reduces risky behaviors in teenagers, such as drug use and unsafe sex. No reports of negative effects from the program have emerged. PAAS, a family-focused program, aims to strengthen African-American families. This approach not only reduces risky behaviors but also supports better school performance. Overall, evidence suggests that PAAS is well-received and effective in making positive changes without causing harm.12345

Why are researchers excited about this trial?

Researchers are excited about the PAAS intervention because it offers a fresh approach to addressing adolescent risky behaviors, especially within African-American families. Unlike standard programs that might focus solely on individual therapy or school-based interventions, PAAS involves the whole family in a series of weekly sessions over six weeks. This family-centered approach aims to build stronger support systems and open communication channels, potentially leading to more lasting behavioral changes. By engaging both adolescents and their families, PAAS hopes to create a more supportive environment that can effectively reduce risky behaviors and improve overall family dynamics.

What evidence suggests that the PAAS intervention is effective for reducing risky behaviors in African-American youth?

Research has shown that the Pathways for African-Americans' Success (PAAS) program helps reduce risky behaviors in African-American youth. In this trial, participants in the experimental arm will complete a 6-week PAAS intervention. Studies have found that PAAS can improve parenting skills and decrease substance use and risky sexual behaviors. Young people in the program are more likely to delay sexual activity and avoid friends who drink or engage in risky sexual activities. The program also encourages racial pride and better parenting, which can help reduce depression in teens. Overall, PAAS has successfully promoted safer behaviors and supported healthier choices in young people.16789

Who Is on the Research Team?

UR

Uma Rao, MD

Principal Investigator

University of California, Irvine

Are You a Good Fit for This Trial?

This trial is for African-American adolescents who can speak and read English, are willing to participate in a 6-week program called PAAS with their guardian, and pass MRI safety checks. It's not for those who are pregnant, claustrophobic, have metal implants, used alcohol or drugs recently, have major medical issues like neurological disorders, take CNS-affecting meds or have clinical-level behavioral problems.

Inclusion Criteria

Subject can speak and read English
Subject and parent/legal guardian agree to participate in the 6-week PAAS program
Subject and parent/legal guardian agree to complete all assessments
See 2 more

Exclusion Criteria

Subject has claustrophobia
I am taking medication that affects my brain or nerves.
Subject has a major medical problem (e.g. neurological disorders)
See 6 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo a 6-week computer-interactive, family-based intervention

6 weeks
6 visits (in-person, weekly)

Follow-up

Participants are monitored for changes in cognitive and emotional regulation post-intervention

3 months
Assessments at baseline and 3 months post-intervention

What Are the Treatments Tested in This Trial?

Interventions

  • Pathways for African-Americans' Success (PAAS)
Trial Overview The study tests the PAAS intervention program designed to reduce risky behaviors among African-American youth. Researchers will look at how this program influences brain regions associated with risk-taking behavior by using MRI scans before and after the program.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Pathways for African-Americans' SuccessExperimental Treatment1 Intervention
Group II: Wait-listActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of California, Irvine

Lead Sponsor

Trials
580
Recruited
4,943,000+

Citations

Pathways for African American Success: Results of Three- ...This study provides evidence of the ability of eHealth to improve parenting and reduce adolescent engagement in substance use and sexual risk behavior.
Effects of the Pathways for African American Success ...We also examined the indirect effects of the PAAS eHealth program on adolescent depression, through improvements in parenting and racial pride. For this model, ...
The Pathways for African American SuccessComparative effectiveness of PAAS interactive conditions versus noninteractive control. ... Preventing drug abuse among adoles- · cent girls: Outcome data from an ...
The Closing Digital Divide - African AmericansThe Pathways for African American Success (PAAS) program was developed as a scalable eHealth preventive intervention to facilitate parents' use of strategies ...
How a tech-based program on health brought African ...Youth who used PAAS through technology alone were more likely to delay sexual onset, and avoid friends who were drinking or sexually active.
6.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/30865782/
Pathways for African American Success: Results of Three-Arm ...This study provides evidence of the ability of eHealth to improve parenting and reduce adolescent engagement in substance use and sexual ...
Program Overview – Paas ResourceidPAAS is a family-based program to build on African American parents' strengths, encouraging children to avoid harmful situations and promoting academic success.
A review of the impact of structural racism on lived ...evaluated The Pathways for African Americans Success (PAAS) program [76]. Results demonstrated positive program effects on racial equity ...
Effects of the Pathways for African American Success ...Our risk model indicated adolescent depression was associated with their own (direct) and their parents' (indirect) experience of discrimination. Mediation ...
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