Personalized Feedback for PTSD and Cannabis Use

TA
Overseen ByTerrell A Hicks, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: VA Office of Research and Development
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Many Veterans live with posttraumatic stress disorder (PTSD) and use cannabis to manage distress, despite limited supportive evidence. Veterans with PTSD who use cannabis often struggle with sleep, physical activity, and social connection, which are factors critical to health and well-being. This project will use smartphones and wearable devices to track symptoms and daily behaviors in real time and provide personalized feedback to help Veterans understand and manage the impact of PTSD and cannabis use in their lives. The study will develop a motivational interviewing-based personalized feedback approach that uses real-time data to help Veterans make data-informed decisions about their mental health, cannabis use, and functional behaviors. Findings will support development of scalable, Veteran-centered tools to promote healthier coping, functional recovery, and quality of life, even if they are not currently in treatment. The goal is to develop supportive, real-time strategies that meet Veterans where they are and promote better outcomes across the VA healthcare system.

Who Is on the Research Team?

TA

Terrell A. Hicks, PhD

Principal Investigator

VA San Diego Healthcare System, San Diego, CA

Are You a Good Fit for This Trial?

This trial is for U.S. military veterans diagnosed with PTSD who use cannabis at least once a week, can read and speak English, own a smartphone, and are willing to use wearable devices for 2 weeks. People can't join if they have severe mental illness (like schizophrenia), high suicide risk, or are in trauma-focused therapy.

Inclusion Criteria

Cannabis use at least once per week over the past 3 months
English-speaking and reading
U.S. Military Veterans
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Exclusion Criteria

I am currently in trauma-focused therapy for PTSD.
Lack of smartphone ownership
Severe substance use disorder (excluding cannabis) due to potential confounding from acute withdrawal or other drug effects; mild/moderate non-cannabis disorders permitted with monitoring
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Phase 1

Development of Personalized Feedback Session (PFS) with 20 participants

14 days
Daily EMA and wearable monitoring

Phase 2

Pilot testing of the first iteration PFS with 10 participants

14 days
Daily EMA and wearable monitoring

Phase 3

Testing of the second iteration PFS with 30 participants

14 days
Daily EMA and wearable monitoring

Follow-up

Participants are monitored for safety and effectiveness after treatment

3 months
1- and 3-month follow-up assessments

What Are the Treatments Tested in This Trial?

Interventions

  • Personalized Feedback Session (PFS)

Trial Overview

The study tests whether personalized feedback sessions using real-time data from smartphones and wearables help veterans with PTSD better understand their symptoms, cannabis use, sleep, activity levels, and social connections. The approach uses motivational interviewing techniques.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Personalized Feedback Session (PFS)Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

VA Office of Research and Development

Lead Sponsor

Trials
1,691
Recruited
3,759,000+