MRI for Heart Failure
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to understand how heart failure might affect the brain. Researchers will use MRI (Magnetic Resonance Imaging) scans to examine brain structures in people with heart failure and compare them to those with normal heart function. The goal is to determine if heart problems could accelerate brain changes, possibly explaining the higher dementia risks in heart failure patients. This trial suits individuals with heart failure, whether hospitalized or not, who have an ejection fraction (a measure of heart pumping ability) below 50%, and do not suffer from severe claustrophobia. As an unphased study, this trial offers a unique opportunity to contribute to groundbreaking research on the link between heart failure and brain health.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What prior data suggests that this MRI protocol is safe for heart failure patients?
Past studies have shown that MRI (Magnetic Resonance Imaging) is very safe for most people. Research indicates that MRIs are even safe for patients with heart devices, like pacemakers, when proper safety steps are followed. Many studies have examined various heart conditions and found that MRIs do not cause harm when used carefully.
These findings suggest that MRI is generally well-tolerated and carries a low risk of side effects. However, discussing any concerns with the research team before joining a study is important. They can provide more details about the MRI process and how they will ensure safety during the trial.12345Why are researchers excited about this trial?
Researchers are excited about using Magnetic Resonance Imaging (MRI) for heart failure because it offers a non-invasive way to get detailed images of the heart, potentially providing insights that standard treatments like medication or surgery can't offer. Unlike traditional methods that focus on symptom management or improving heart function through drugs or devices, MRI can help identify the underlying causes of heart failure with precision. This could lead to more personalized treatment plans and better outcomes for patients, as doctors can tailor interventions based on specific heart conditions revealed by the MRI.
What evidence suggests that this MRI protocol is effective for studying brain changes in heart failure patients?
Research has shown that Magnetic Resonance Imaging (MRI) aids in understanding heart failure. In this trial, participants will be divided into two groups: those hospitalized due to heart failure and those who were not. Studies have found that cardiac MRI detects new heart issues in about 27% of people with heart failure. This detection helps doctors predict risks such as death and serious heart problems. MRI also identifies changes in the brain related to heart function. This is crucial because heart failure is linked to brain changes that might affect memory and thinking. MRI can further explore these connections.678910
Who Is on the Research Team?
Joao AC Lima, MD
Principal Investigator
Johns Hopkins University
Are You a Good Fit for This Trial?
This trial is for adults over 21 who can walk on their own and have heart failure with an ejection fraction below 50%. They must not be claustrophobic to undergo MRI scans. Participants need to give informed consent.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Imaging Assessment
Participants undergo MRI to measure subcortical brain volumes and assess cardiac parameters
Follow-up
Participants are monitored for changes in subcortical volumes and cardiac function
What Are the Treatments Tested in This Trial?
Interventions
- Magnetic Resonance Imaging
Find a Clinic Near You
Who Is Running the Clinical Trial?
Johns Hopkins University
Lead Sponsor
Canon Medical Systems, USA
Industry Sponsor