32 Participants Needed

Exercise for Osteoarthritis

GH
Overseen ByGillian Hatfield, PhD
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: University of the Fraser Valley
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if a 12-week exercise program can improve balance in individuals with knee osteoarthritis, a condition that causes joint pain and stiffness. Participants will attend exercise classes twice a week, focusing on flexibility, strength, and coordination, with adjustable intensity options. The trial seeks individuals with knee osteoarthritis who have been cleared to begin an exercise program. As an unphased trial, this study offers a unique opportunity to contribute to research that may enhance the quality of life for those with knee osteoarthritis.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It focuses on exercise for knee osteoarthritis and does not mention medication changes.

What prior data suggests that this exercise program is safe for people with knee osteoarthritis?

Research has shown that exercise programs for knee osteoarthritis are generally safe. A review of studies found no significant safety differences between those who exercised and those who did not, indicating that exercising does not lead to more negative side effects. Another study on app-based exercise programs for osteoarthritis also found them safe and effective. Additionally, an 8-week mindful exercise program proved safe for individuals with knee osteoarthritis. Overall, these findings suggest that exercise programs, like the one in this study, are well-tolerated and safe for people with knee osteoarthritis.12345

Why are researchers excited about this trial?

Most treatments for osteoarthritis focus on pain relief through medications like NSAIDs or injections. However, this new exercise program is unique because it emphasizes a non-pharmacological approach, promoting physical activity that can enhance joint function and overall well-being without the side effects of drugs. Researchers are excited about this treatment because it offers a holistic way to manage osteoarthritis symptoms, potentially delaying disease progression and improving quality of life for patients. By encouraging regular, guided exercise, this intervention might not only reduce pain but also increase strength and mobility, offering long-term benefits beyond what conventional treatments provide.

What evidence suggests that this exercise program is effective for improving balance in knee osteoarthritis?

Studies have shown that exercise can greatly help people with knee osteoarthritis by reducing pain, improving joint function, and enhancing overall quality of life. In this trial, participants will engage in a 12-week exercise program. Research indicates that such programs can lead to better balance, improved walking, and less joint stiffness. Different types of exercises, including stretching, strengthening, and coordination, contribute to these benefits. Overall, exercise offers a promising way to manage knee osteoarthritis effectively.15678

Who Is on the Research Team?

GH

Gillian Hatfield, PhD

Principal Investigator

University of the Fraser Valley

Are You a Good Fit for This Trial?

This trial is for adults with knee osteoarthritis who can attend two sessions at the University of the Fraser Valley and commit to a 12-week exercise program. The program includes classes twice per week, adaptable to various fitness levels.

Inclusion Criteria

Pass the Get Active Questionnaire to ensure that they are safe to begin an exercise program
I have been diagnosed with knee osteoarthritis by a doctor.

Exclusion Criteria

I have active joint inflammation.
I have a condition like Parkinson's, Alzheimer's, diabetes, or balance issues.
I have vision problems that affect my balance.
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants complete a 12-week exercise program designed for adults with osteoarthritis, attending classes twice per week

12 weeks
2 visits (in-person) at the start and end of the program

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Group Exercise Intervention
Trial Overview The study tests whether a 12-week group exercise program, consisting of flexibility, strength, and coordination exercises, can improve balance in people with knee osteoarthritis. Participants will track their progress through questionnaires and balance tests.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Exercise programExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of the Fraser Valley

Lead Sponsor

Trials
4
Recruited
290+

Published Research Related to This Trial

In a randomized controlled trial involving 209 elderly participants (average age 80), a home-based exercise program was found to be generally safe, with 151 adverse events reported, affecting 47% of participants.
Despite the program's safety, 14% of the adverse events were serious, highlighting that high levels of pre-existing morbidity in this population can pose challenges to maintaining consistent exercise participation.
Adverse events in mobility-limited and chronically ill elderly adults participating in an exercise intervention study supported by general practitioner practices.Hinrichs, T., Bรผcker, B., Wilm, S., et al.[2015]
In a review of over 5,500 participants from 11 physical activity interventions, no serious study-related adverse events were reported, indicating a high level of safety in these exercise programs.
While minor musculoskeletal injuries were noted, the studies emphasized a 'start low and go slow' approach, suggesting that moderate-intensity physical activity is safe and effective for sedentary, chronically ill, or older populations.
Screening, safety, and adverse events in physical activity interventions: collaborative experiences from the behavior change consortium.Ory, M., Resnick, B., Jordan, PJ., et al.[2022]
In a review of 113 randomized controlled trials involving 5909 participants with knee osteoarthritis, only 44.2% reported adverse events (AEs), indicating potential underreporting of exercise-related harm, which was found in 6.0% of participants with clear AE statements.
The study highlighted improvements in reporting AEs and dropouts (DOs) after the implementation of the CONSORT-2010 guidelines, but emphasized the need for clearer definitions and reporting standards to ensure the safety and efficacy of therapeutic exercise interventions.
Reporting of Harm in Randomized Controlled Trials of Therapeutic Exercise for Knee Osteoarthritis: A Systematic Review.von Heideken, J., Chowdhry, S., Borg, J., et al.[2023]

Citations

Effectiveness of exercise therapy in patients with knee ...This study aimed to assess the methodological quality of published systematic reviews of exercise therapy in knee osteoarthritis and summarise ...
systematic review and network meta-analysisThe findings demonstrated that exercise was effective at improving pain, function, gait performance, and quality of life in individuals with ...
Group physical therapy for knee osteoarthritis: protocol for a ...The Group PT program has strong potential to become a standard offering for PT, improving function and pain-related outcomes for patients with ...
Exercise Therapy for Knee Osteoarthritis: A Systematic ...All 5 types of exercise were able to ameliorate KOA. AE (for pain relief) and YG (for joint stiffness, limited knee function, and quality of ...
Efficacy of the mHealth-Based Exercise Intervention re.flex for ...Objective: This study aims to evaluate the efficacy of a 12-week fully automated app-based exercise intervention with and without a supporting ...
The Effect and Safety of App-Based Interventions for ...This study showed that app-based interventions were safe and effective for patients with OA, which might provide a cost-effective option, ...
Walking, cycling and swimming likely best exercise for ...None of the exercise interventions resulted in more adverse safety events than the control group, suggesting that exercise therapy is a safe ...
Telehealth mindful exercise for people with knee ...Conclusion. An 8-week telehealth, group-based, mindful exercise intervention was safe for people with knee OA. Our decentralized approach was feasible in terms ...
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