30 Participants NeededMy employer runs this trial

Latanoprost for Glaucoma

HA
FD
Overseen ByFarzaneh Dadvar, MD
Age: 18+
Sex: Any
Trial Phase: Phase < 1
Sponsor: Johns Hopkins University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Persons who do not have glaucoma will have pictures taken of the optic nerve with a standard camera before and 2 weeks after starting to take a daily glaucoma eye drop to lower eye pressure. These data will be used to compare to the same procedure performed with glaucoma patients to study how glaucoma injures the eye.

Who Is on the Research Team?

HQ

Harry Quigley, MD

Principal Investigator

Johns Hopkins University

Are You a Good Fit for This Trial?

This trial is for adults over 30 who do not have glaucoma, have healthy eye exams and scans, and no signs of optic nerve damage. Both men and women from any ethnic background can join if their eyes are healthy.

Inclusion Criteria

I am eligible regardless of my sex.
I have optic nerve damage or optic neuropathy.
All ethnic groups
See 6 more

Exclusion Criteria

I have an eye condition that prevents clear imaging of my eye.
Lack of reliable clinical Optical Coherence Tomography (OCT) testing
I have had eye surgery or corneal problems that affect accurate eye pressure readings.
See 6 more

What Are the Treatments Tested in This Trial?

Interventions

  • Latanoprost

Trial Overview

The study tests the effect of daily Latanoprost (an eye drop that lowers eye pressure) on the optic nerve in people without glaucoma. Pictures of the optic nerve are taken before starting drops and after two weeks to see changes.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Study groupExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Johns Hopkins University

Lead Sponsor

Trials
2,366
Recruited
15,160,000+

National Eye Institute (NEI)

Collaborator

Trials
572
Recruited
1,320,000+