Scott Michael Schuetze MD, PhD - SFA

Dr. Scott Schuetze, MD, PhD

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University of Michigan Comprehensive Cancer Center

Studies Liposarcoma
Studies Soft Tissue Sarcoma
11 reported clinical trials
17 drugs studied

Area of expertise

1

Liposarcoma

Scott Schuetze, MD, PhD has run 3 trials for Liposarcoma. Some of their research focus areas include:

Stage IV
Stage III
MDM2 positive
2

Soft Tissue Sarcoma

Scott Schuetze, MD, PhD has run 3 trials for Soft Tissue Sarcoma. Some of their research focus areas include:

Stage IV
Stage III
FGFR positive

Affiliated Hospitals

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University Of Michigan Comprehensive Cancer Center

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University Of Michigan

Clinical Trials Scott Schuetze, MD, PhD is currently running

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Itraconazole + Ablation

for Preventing Esophageal Cancer

This phase II trial tests how well itraconazole works in combination with the usual standard of care endoscopy with ablation for the prevention of esophageal cancer in patients who have high-risk Barrett's esophagus (BE). BE is a condition in which the lining of the esophagus changes and becomes more like the tissue that lines the intestine. People with Barrett's esophagus have a higher risk of developing esophageal cancer. Itraconazole is a drug used to prevent or treat fungal infections. Ablation refers to the removal of abnormal tissue using heat. Endoscopy is a procedure for looking at the esophagus using a long, flexible tube called an endoscope, which has a video camera at the end. Radiofrequency ablation is a type of heat therapy that uses radiofrequency energy (similar to microwave heat) to destroy the abnormal tissue in the esophagus. Giving itraconazole in combination with standard of care endoscopy with ablation may improve the effects of ablation and prevent esophageal cancer in patients with high-risk Barrett's esophagus.

Recruiting

0 awards

Phase 2

5 criteria

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Low-Dose Chemotherapy + Anti-Cancer Drug

for Sarcoma

This phase I trial tests the safety, side effects, and best dose of combination therapy with liposomal doxorubicin and peposertib in treating patients with sarcoma that has spread from where it first started, to other places in the body (metastatic), or cannot be removed by surgery (unresectable) and for which no known cure is available (advanced). Doxorubicin is in a class of medications called anthracyclines. Doxorubicin damages the cell's deoxyribonucleic acid (DNA) and may kill cancer cells. It also blocks a certain enzyme needed for cell division and DNA repair. Liposomal doxorubicin is a form of the anticancer drug doxorubicin that is contained inside very tiny, fat-like particles. Liposomal doxorubicin may have fewer side effects and work better than other forms of the drug. Peposertib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It may also enhance the activity of chemo- and radiotherapy. There is some pre-clinical evidence in animal models that combining peposertib with liposomal doxorubicin can shrink or stabilize certain types of cancer for longer than either drug alone, but it is not known if this will happen in people. Combination therapy with liposomal doxorubicin and peposertib may be effective in treating patients with advanced sarcoma.

Recruiting

1 award

Phase 1

More about Scott Schuetze, MD, PhD

Clinical Trial Related

4 years of experience running clinical trials · Led 11 trials as a Principal Investigator · 3 Active Clinical Trials

Treatments Scott Schuetze, MD, PhD has experience with

  • Nivolumab
  • Doxorubicin
  • BI 907828
  • Paclitaxel
  • Rogaratinib
  • Pegylated Liposomal Doxorubicin Hydrochloride

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