Éric Turcotte - Spécialistes ...

Dr. Éric Turcotte, MD

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Centre de recherche du CHUS

Studies Bone Disease
Studies Bone Cancer
6 reported clinical trials
9 drugs studied

Affiliated Hospitals

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Centre De Recherche Du CHUS

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CHUS

Clinical Trials Éric Turcotte, MD is currently running

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Afternoon vs Morning Exercise

for Prediabetes

Exercise is well-known to improve skeletal muscle energy metabolism and is an established intervention to improve muscle insulin sensitivity and to counter the development of type 2 diabetes (T2D). However, given the 24h rhythmicity in substrate metabolism previously observed in healthy, lean men and the lack of such rhythmicity in men with insulin-resistance, the investigator hypothesize that appropriate timing of exercise training can maximize the metabolic health effects of exercise. Indeed, a preliminary study in humans revealed that afternoon high-intensity interval training (HIIT) exercise was more effective than morning exercise in improving 24h blood glucose levels in men with T2D. Another recent study in mice showed that the time of day is a critical factor in augmenting the beneficial effects of exercise on the skeletal muscle metabolome as well as on whole-body energy homeostasis. However, human studies that specifically target the impact of timing of exercise training on glucose homeostasis and metabolic health are scarce and the potential underlying mechanisms largely unknown. The overarching goals of this project is to improve 24-hour rhythmicity of metabolism in men and women with prediabtes by appropriate timing of exercise and to assess its effect on metabolic health and immune response. Acute and prolonged exercise interventions timed in the morning vs late afternoon will be carried out in individuals with prediabetes to determine whether acute exercise in the afternoon and prolonged exercise training in the afternoon can improve peripheral insulin sensitivity, compared to exercise in the morning, and positively affect adipose tissue dietary fatty acid storage and partitioning of dietary fatty acids in skeletal muscles.

Recruiting

1 award

N/A

4 criteria

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68Ga-DOTA-TATE Imaging

for Neuroendocrine Cancer

This clinical trial is a pragmatic study aiming to evaluate the innocuity/safety profile of the PET radiotracer 68Ga-DOTA-TATE, and to establish the procedure as a routine standard-of-care diagnostic tool for all neuro-endocrine cancer patients. It is a single-center study, but with recruitment across all Canada. The trial is prospective, non-randomized, open-label and with no control group. The superiority of this procedure over the former standard-of-care (Octreoscan) was already established in previous and numerous studies across the world. As such, the current trial aims to gather data to further support the implementation of 68Ga-DOTA-TATE as the new standard-of-care for neuro-endocrine tumors (NET).

Recruiting

2 awards

Phase 3

3 criteria

More about Éric Turcotte, MD

Clinical Trial Related

2 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Éric Turcotte, MD has experience with

  • 18F-sodium Fluoride
  • 68Ga-DOTA-TATE
  • 4FMFES
  • [111In]-FPI-2107
  • [225Ac]-FPI-2068
  • FPI-2053

Breakdown of trials Éric Turcotte, MD has run

Rotator Cuff Arthropathy

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