Nikolai A. Podoltsev, MD, PhD ...

Dr. Nikolai A. Podoltsev

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Yale University

Studies Acute Myeloid Leukemia
Studies Chronic Myelomonocytic Leukemia
6 reported clinical trials
27 drugs studied

Area of expertise

1

Acute Myeloid Leukemia

Nikolai A. Podoltsev has run 3 trials for Acute Myeloid Leukemia. Some of their research focus areas include:

FLT3 positive
D835 positive
2

Chronic Myelomonocytic Leukemia

Nikolai A. Podoltsev has run 2 trials for Chronic Myelomonocytic Leukemia.

Affiliated Hospitals

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Yale University

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Yale Cancer Center

Clinical Trials Nikolai A. Podoltsev is currently running

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Inotuzumab Ozogamicin + Chemotherapy

for Leukemia

This phase III trial studies the side effects of inotuzumab ozogamicin and how well it works when given with frontline chemotherapy in treating patients with newly diagnosed B acute lymphoblastic leukemia. Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a chemotherapy drug called ozogamicin. Inotuzumab is a form of targeted therapy because it attaches to specific molecules (receptors) on the surface of cancer cells, known as CD22 receptors, and delivers ozogamicin to kill them. Chemotherapy drugs, such as \[intervention\], work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving inotuzumab ozogamicin with chemotherapy may work better in treating young adults with B acute lymphoblastic leukemia.

Recruiting

2 awards

Phase 3

3 criteria

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Tuspetinib

for Acute Myeloid Leukemia

The main purpose of this study is to identify a safe and potentially effective dose of tuspetinib to be used in future studies in study participants diagnosed with acute myeloid leukemia (AML), myelodysplastic syndromes with increased blasts grade 2 (MDS-IB2), or chronic myelomonocytic leukemia (CMML) that is relapsed or refractory after at least one line of prior therapy, or in study participants with newly diagnosed AML. Tuspetinib will be administered as a single agent or in combination with other drugs (venetoclax or venetoclax plus azacitidine), as specified for each part of the study.

Recruiting

1 award

Phase 1 & 2

22 criteria

More about Nikolai A. Podoltsev

Clinical Trial Related

5 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Nikolai A. Podoltsev has experience with

  • Venetoclax
  • Cyclophosphamide
  • Cytarabine
  • Dexamethasone
  • Methotrexate
  • Vincristine Sulfate

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