Neha Mehta-Shah, MD, MSCI - Washington ...

Dr. Neha Mehta-shah, M.D.

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Washington University School of Medicine

Studies Lymphoma
Studies Sezary Syndrome
19 reported clinical trials
34 drugs studied

About Neha Mehta-shah, M.D.

Education:

  • MD from Feinberg School of Medicine, Northwestern University, Chicago, IL (2005-2009).
  • Masters of Science in Clinical Investigation (MSCI) from Washington University in St. Louis, MO (2016-2019).
  • BA in Psychology (Cum Laude) from Northwestern University, Evanston, IL (2002-2005).

Experience:

  • Assistant Professor of Medicine at Washington University in St. Louis, specializing in peripheral and cutaneous T-cell lymphomas.
  • Fellow in Hematology/Oncology at Memorial Sloan Kettering Cancer Center, New York, NY (2013-2016).
  • Chief Medical Resident at Memorial Sloan Kettering Cancer Center, New York, NY (2012-2013).
  • Resident in Internal Medicine at New York Presbyterian-Weill Cornell Medical Center, New York, NY (2009-2012).

Area of expertise

1

Lymphoma

Neha Mehta-shah, M.D. has run 7 trials for Lymphoma. Some of their research focus areas include:

Stage IV
CD7 positive
IDH positive
2

Sezary Syndrome

Neha Mehta-shah, M.D. has run 5 trials for Sezary Syndrome. Some of their research focus areas include:

Stage II
Stage III
Stage IV

Affiliated Hospitals

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Washington University School Of Medicine

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Siteman Cancer Center At West County Hospital

Clinical Trials Neha Mehta-shah, M.D. is currently running

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Thiotepa + Stem Cell Transplant

for Lymphoma

A serious consequence of systemic diffuse large B-cell lymphoma (DLBCL) is secondary central nervous system (CNS) relapse, which occurs in approximately 5% of all patients. Many CNS relapses occur within the first year after completion of frontline treatment and are associated with significantly increased mortality; thus, it is important to tailor frontline treatment to provide prophylaxis against CNS relapse in those patients who are determined to be high-risk. Autologous stem cell transplantation (ASCT) is standard of care for patients with DLBCL who relapse one year or more after first remission, and it has been shown to improve progression-free survival for patients with primary CNS lymphoma. The four-drug BEAM regimen (carmustine, etoposide, cytarabine, and melphalan) is the preferred conditioning regimen for DLBCL patients undergoing ASCT; however, patients with primary CNS lymphoma receive thiotepa plus carmustine as their conditioning regimen due to its better CNS penetration. This study tests the hypothesis that consolidation thiotepa/carmustine ASCT in first complete remission will reduce the risk of CNS relapse in transplant-eligible patients with DLBCL with no prior CNS disease at high risk of secondary CNS recurrence.

Recruiting

1 award

Phase 2

3 criteria

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Duvelisib/CC-486 + Chemotherapy

for Lymphoma

This phase II trial studies the effect of duvelisib or CC-486 and usual chemotherapy consisting of cyclophosphamide, doxorubicin, vincristine, etoposide, and prednisone in treating patients with peripheral T-cell lymphoma. Duvelisib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as CC-486, cyclophosphamide, doxorubicin, vincristine, etoposide and prednisone, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial may help find out if this approach is better or worse than the usual approach for treating peripheral T-cell lymphoma.

Recruiting

1 award

Phase 2

27 criteria

More about Neha Mehta-shah, M.D.

Clinical Trial Related

5 years of experience running clinical trials · Led 19 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Neha Mehta-shah, M.D. has experience with

  • Nivolumab
  • Rituximab
  • Duvelisib
  • Mosunetuzumab
  • Acalabrutinib
  • Durvalumab

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