Dr. Mari H Dallas, MD

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UH Rainbow Babies and Children's Hospital (University Hospitals Cleveland Medical Center)

Studies Opportunistic Infections
Studies Bone Marrow Transplant
3 reported clinical trials
11 drugs studied

Affiliated Hospitals

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UH Rainbow Babies And Children's Hospital (University Hospitals Cleveland Medical Center)

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University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center

Clinical Trials Mari H Dallas, MD is currently running

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T Cell Therapy

for Cytomegalovirus

The purpose of this study is to determine if a specific type of cell-based immunotherapy, using T-cells from a donor that are specific against cytomegalovirus (CMV) is feasible to treat infections by CMV. Adoptive T-cell therapy is an investigational (experimental) therapy that works by using the blood of a donor and selecting the T-cells that can respond against a specific infectious entity. These selected T-cells are then infused to the patient, to try to give the immune system the ability to fight the infection. Adoptive T-cell therapy is experimental because it is not approved by the Food and Drug Administration (FDA).

Recruiting

1 award

Phase < 1

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Adoptive T Cell Therapy

for Adenovirus Infections After Bone Marrow Transplant

The purpose of this study is to determine if it is possible to treat an infection with a cell-based immunotherapy (therapy that uses the patient's own immune system to treat the infection). This treatment is called adoptive T cell therapy. Another purpose is to learn about the side effects and toxicities of adoptive T cell therapy. Adoptive T cell therapy is an investigational (experimental) therapy that works by using the blood of a donor that has immunity against the virus. The donor cells are collected and then the cells, called T cells, that are capable of defending against the virus are selected out. These selected T cells are then infused back into the patient, to try to give the immune system the ability to fight the infection. Adoptive T cell therapy is experimental because it is not approved by the Food and Drug Administration (FDA).

Recruiting

1 award

Phase < 1

More about Mari H Dallas, MD

Clinical Trial Related

7 years of experience running clinical trials · Led 3 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Mari H Dallas, MD has experience with

  • IFN-gamma-secreting HAdV Antigen Specific T Cells
  • CMV Specific Adoptive T-cells
  • Allogeneic Bone Marrow Transplantation
  • Busulfan
  • Cyclophosphamide
  • Fludarabine

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