Jill M Wecht | Mount Sinai - New York

Dr. Jill M Wecht, EdD

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James J. Peters VA Medical Center, Bronx, NY

Studies Spinal Cord Injury
Studies Orthostatic Hypotension
7 reported clinical trials
8 drugs studied

Affiliated Hospitals

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James J. Peters VA Medical Center, Bronx, NY

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James J Peters VAMC

Clinical Trials Jill M Wecht, EdD is currently running

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TSCS

for Spinal Cord Injury

This project will focus on a novel approach to stabilizing blood pressure (BP) during inpatient rehabilitation after acute SCI. After SCI, people have unstable blood pressure, ranging from too low (orthostatic hypotension) to too high (autonomic dysreflexia). Unstable BP often interferes with performing effective physical rehabilitation after SCI. A critical need exists for the identification of safe, practical and effective treatment options that stabilize BP after traumatic SCI. Transcutaneous Spinal Cord Stimulation (TSCS) has several advantages over pharmacological approaches: (1) does not exacerbate polypharmacy, (2) can be activated/deactivated rapidly, and (3) can be applied in synergy with physical exercise. The study team is asking the key question: "What if applying TSCS earlier after injury could prevent the development of BP instability?" To facilitate adoption of TSCS for widespread clinical use, the study team plans to map and develop a parameter configuration that will result in an easy to follow algorithm to maximize individual benefits, while minimizing the burden on healthcare professionals. This project will provide the foundational evidence to support the feasible and safe application of TSCS in the newly injured population, thereby overcoming barriers to engagement in prescribed inpatient rehabilitation regimens that are imposed by BP instability.

Recruiting

1 award

N/A

4 criteria

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Midodrine

for Low Blood Pressure

The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals with SCI.

Recruiting

3 awards

Phase 4

More about Jill M Wecht, EdD

Clinical Trial Related

3 years of experience running clinical trials · Led 7 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Jill M Wecht, EdD has experience with

  • Midodrine Hydrochloride
  • DS8R
  • Sham Transcutaneous Spinal Cord Stimulation
  • Transcutaneous Spinal Cord Stimulation (TSCS)
  • Placebo
  • Mirabegron

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