Dr. Jennifer G. Michlitsch
Claim this profileUCSF Benioff Children's Hospital Oakland
About Jennifer G. Michlitsch
Education:
- Obtained MD (Doctor of Medicine) from the University of California, San Francisco (UCSF) in 2010.
- Completed Residency in Pediatrics at UCSF Benioff Children's Hospital Oakland in 2013.
- Finished Fellowship in Pediatric Hematology/Oncology at UCSF Benioff Children's Hospital Oakland in 2016.
Experience:
- Currently serving as an attending physician in the Division of Hematology/Oncology at UCSF Benioff Children's Hospital Oakland.
Area of expertise
Cancer
Jennifer G. Michlitsch has run 7 trials for Cancer. Some of their research focus areas include:
Langerhans Cell Histiocytosis
Jennifer G. Michlitsch has run 5 trials for Langerhans Cell Histiocytosis. Some of their research focus areas include:
Affiliated Hospitals
UCSF Benioff Children's Hospital Oakland
UCSF Medical Center-Mission Bay
Clinical Trials Jennifer G. Michlitsch is currently running
Inotuzumab Ozogamicin
for Acute Lymphoblastic Leukemia
This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy and immunotherapy (chemo-immunotherapy) for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. Inotuzumab ozogamicin is a monoclonal antibody, which is a type of protein that can bind to certain targets on the surface of cells. Inotuzumab ozogamicin is a monoclonal antibody that is linked to a type of chemotherapy called calicheamicin. Inotuzumab attaches to cancer cells by binding to the CD22 protein on the surface of the cancer cell and delivering calicheamicin inside the cells to kill them. Other drugs used in the chemotherapy regimen, such as cyclophosphamide, cytarabine, dexamethasone, doxorubicin, daunorubicin, methotrexate, leucovorin, mercaptopurine, prednisone, thioguanine, vincristine, and pegaspargase or calaspargase pegol work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Blinatumomab is a specialized type of monoclonal antibody known as a bispecific T-cell engager (BiTE). It works by simultaneously binding to CD19 on cancer cells and CD3 on normal immune cells, bringing them together to destroy leukemia cells. Blinatumomab is a standard part of chemo-immunotherapy treatment for B-ALL. This trial also studies the outcomes of patients with mixed phenotype acute leukemia (MPAL), and B-lymphoblastic lymphoma (B-LLy) when treated with ALL therapy without inotuzumab ozogamicin or blinatumomab. The overall goal of this study is to understand if adding inotuzumab ozogamicin to standard of care chemo-immunotherapy maintains or improves outcomes in High Risk B-cell Acute Lymphoblastic Leukemia (HR B-ALL). The first part of the study includes the first phase of therapy: Induction. This part will collect information on the leukemia, as well as the effects of the initial treatment, to classify patients into post-induction treatment groups. On the second part of this study, patients with HR B-ALL will receive the remainder of the chemotherapy cycles (consolidation, blinatumomab block 1, interim maintenance 1, blinatumomab block 2, delayed intensification, interim maintenance 2, maintenance), with some patients randomized to receive inotuzumab. The patients that receive inotuzumab will not receive part of consolidation or part of delayed intensification. Other aims of this study include evaluating 1) side effects of treatment using patient-reported outcomes and health-related quality of life, 2) the best ways to help patients adhere to oral chemotherapy regimens, 3) the relationship between levels of inotuzumab ozogamicin in the blood and side effects, 4) the impact of chemo-immunotherapy on the immune system and risk of infection, and 5) the impact of social determinants of health on outcomes. Finally, this study will be the first to track the outcomes of subjects with disseminated B-cell Lymphoblastic Leukemia (B-LLy) or Mixed Phenotype Acute Leukemia (MPAL) when treated with B-ALL chemotherapy.
Recruiting
2 awards
Phase 3
Health Study After Leukemia Treatment
for People With Down Syndrome
This study attempts to learn more about the health of persons with Down syndrome after treatment for acute leukemia. Children with Down syndrome are at increased risk for side effects during treatment for acute leukemia, but it is unclear of their risk for long-term effects of cancer treatment. By learning more about the factors that may contribute to chronic health conditions and long-term effects after treatment for leukemia in persons with Down syndrome, clinical practice guidelines for survivorship care can be developed to help improve their quality-of-life.
Recruiting
1 award
N/A
10 criteria
More about Jennifer G. Michlitsch
Clinical Trial Related
9 years of experience running clinical trials · Led 23 trials as a Principal Investigator · 11 Active Clinical Trials
Treatments Jennifer G. Michlitsch has experience with
- Cyclophosphamide
- Methotrexate
- Mercaptopurine
- Prednisolone
- Pegaspargase
- Dexamethasone
Breakdown of trials Jennifer G. Michlitsch has run
Cancer
Langerhans Cell Histiocytosis
Biphenotypic Leukemia
Burkitt's Leukemia
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Jennifer G. Michlitsch specialize in?
Jennifer G. Michlitsch focuses on Cancer and Langerhans Cell Histiocytosis. In particular, much of their work with Cancer has involved Stage I patients, or patients who are Stage II.
Is Jennifer G. Michlitsch currently recruiting for clinical trials?
Yes, Jennifer G. Michlitsch is currently recruiting for 11 clinical trials in Oakland California. If you're interested in participating, you should apply.
Are there any treatments that Jennifer G. Michlitsch has studied deeply?
Yes, Jennifer G. Michlitsch has studied treatments such as Cyclophosphamide, Methotrexate, Mercaptopurine.
What is the best way to schedule an appointment with Jennifer G. Michlitsch?
Apply for one of the trials that Jennifer G. Michlitsch is conducting.
What is the office address of Jennifer G. Michlitsch?
The office of Jennifer G. Michlitsch is located at: UCSF Benioff Children's Hospital Oakland, Oakland, California 94609 United States. This is the address for their practice at the UCSF Benioff Children's Hospital Oakland.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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