Janice Mehnert, MD | NYU Langone Health

Dr. Janice M. Mehnert

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Laura and Isaac Perlmutter Cancer Center at NYU Langone

Studies Melanoma
Studies Cancer
18 reported clinical trials
26 drugs studied

About Janice M. Mehnert

Education:

  • Holds an MD (Doctor of Medicine).

Experience:

  • Faculty member in the Department of Medicine at NYU Langone Health.
  • Serves as the Associate Director of Clinical Research at the Perlmutter Cancer Center.
  • Recognized internationally for expertise in early phase clinical trials, especially in skin cancer and advanced cancers.
  • Plays a key role in the leadership team at Perlmutter Cancer Center.
  • Specializes in skin cancer and phase 1 clinical trials for advanced cancers, with efforts to expand clinical trials across multiple locations.

Area of expertise

1

Melanoma

Janice M. Mehnert has run 9 trials for Melanoma. Some of their research focus areas include:

Stage IV
Stage III
BRAF positive
2

Cancer

Janice M. Mehnert has run 8 trials for Cancer. Some of their research focus areas include:

Stage IV
PD-L1 positive
BRAF positive

Affiliated Hospitals

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Laura And Isaac Perlmutter Cancer Center At NYU Langone

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NYU Langone Health

Clinical Trials Janice M. Mehnert is currently running

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GV20-0251

for Cancer

This is a Phase 1/2A study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved therapies or other standard of care.

Recruiting

1 award

Phase 1 & 2

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Nivolumab

for Cancer

This phase Ib trial studies the side effects of nivolumab and to see how well it works alone and in combination with other treatments, such as ipilimumab, cabozantinib, platinum containing therapy, and fluoropyrimidine, in treating patients with autoimmune disorders and cancer that has spread from where it first started (primary site) to nearby tissue, lymph nodes, or distant parts of the body (advanced), to other places in the body (metastatic) or cannot removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Cabozantinib blocks certain proteins, which may help keep tumor cells from growing. It may also prevent the growth of new blood vessels that tumors need to grow. Cabozantinib is a type of tyrosine kinase inhibitor and a type of angiogenesis inhibitor. Chemotherapy drugs, such as platinum containing therapies and fluoropyrimidine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving nivolumab alone and in combination with other treatments, including ipilimumab, cabozantinib, platinum containing therapy, or fluoropyrimidine, may be safe, tolerable, and/or effective in treating patients with autoimmune disorders and advanced, metastatic, or unresectable cancer.

Recruiting

1 award

Phase 1

20 criteria

More about Janice M. Mehnert

Clinical Trial Related

5 years of experience running clinical trials · Led 18 trials as a Principal Investigator · 3 Active Clinical Trials

Treatments Janice M. Mehnert has experience with

  • Nivolumab
  • Ipilimumab
  • Pembrolizumab
  • RP1
  • Trametinib
  • Laboratory Biomarker Analysis

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