Fariba Navid, MD | Children's Hospital ...

Dr. Fariba Navid, MD

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Children's Hospital Los Angeles

Expert in Cancer
Expert in Osteosarcoma
29 reported clinical trials
40 drugs studied

About Fariba Navid, MD

Education:

  • Earned an MD from Tulane Medical School, New Orleans, Louisiana.
  • Completed a Clinical Fellowship in Pediatric Oncology at the National Cancer Institute, Bethesda, MD.

Experience:

  • Serves as Assistant Director of the Clinical Trials Program and COG Phase I & Pilot Consortium at Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles (CHLA) since September 2016.
  • Holds the position of Associate Professor of Clinical Pediatrics at the Keck School of Medicine, University of Southern California.
  • Has extensive experience in research and pediatric early-phase drug development, including previous work at St. Jude Children's Research Hospital.

Area of expertise

1

Cancer

Global Leader

Fariba Navid, MD has run 22 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage I
Stage II
2

Osteosarcoma

Global Leader

Fariba Navid, MD has run 16 trials for Osteosarcoma. Some of their research focus areas include:

Stage IV
Stage I
Stage II

Affiliated Hospitals

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Children's Hospital Los Angeles

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Children's Hospital Of Los Angeles

Clinical Trials Fariba Navid, MD is currently running

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CBL0137

for Cancer

This trial tests CBL0137, a drug that blocks signals inside cancer cells, in patients whose solid tumors, including CNS tumors or lymphoma, have returned or not responded to treatment. By interfering with the cells' internal communication, the drug aims to stop their growth and cause them to die. CBL0137, also known as Curaxin, has shown antitumor activity in multiple cancers, including glioblastoma, renal cell carcinoma, melanoma, neuroblastoma, and small cell lung cancer.

Recruiting

1 award

Phase 1 & 2

13 criteria

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NK Cells + Chemotherapy

for Sarcoma

The purpose of this study is to determine if the addition of infusions of a type of immune cell called a "natural killer", or NK cell to the sarcoma chemotherapy regimen GEM/DOX (gemcitabine and docetaxel) can improve outcomes in people with childhood sarcomas that have relapsed or not responded to prior therapies. The goals of this study are: * To determine the safety and efficacy of the addition of adoptive transfer of universal donor, TGFβ imprinted (TGFβi), expanded NK cells to the pediatric sarcoma salvage chemotherapeutic regimen gemcitabine/docetaxel (GEM/DOX) for treatment of relapsed and refractory pediatric sarcomas To determine the 6-month progression free survival achieved with this treatment in patients within cohorts of relapsed or refractory osteosarcoma, Ewing sarcoma, rhabdomyosarcoma and non-rhabdomyosarcoma soft tissue sarcoma. * To identify toxicities related to treatment with GEM/DOX + TGFβi expanded NK cells Participants will receive study drugs that include chemotherapy and NK cells in cycles; each cycle is 21 days long and you can receive up to 8 cycles. * Gemcitabine (GEM): via IV on Days 1 and 8 * Docetaxel (DOX): via IV on Day 8 * Prophylactic dexamethasone: Day 7-9 to prevent fluid retention and hypersensitivity reaction * Peg-filgrastim (PEG-GCSF) or biosimilar: Day 9 to help your white blood cell recover and allow more chemotherapy to be given * TGFβi NK cells: via IV on Day 12

Recruiting

1 award

Phase 1 & 2

More about Fariba Navid, MD

Clinical Trial Related

3 years of experience running clinical trials · Led 29 trials as a Principal Investigator · 5 Active Clinical Trials

Treatments Fariba Navid, MD has experience with

  • Larotrectinib
  • Palbociclib
  • Erdafitinib
  • Selpercatinib
  • Tipifarnib
  • Vemurafenib

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