Dr. Darin Dougherty, MD
Claim this profileMassachusetts General Hospital
Affiliated Hospitals
Massachusetts General Hospital
Massachussetts General Hospital
Clinical Trials Darin Dougherty, MD is currently running
Focused Ultrasound
for Anxiety
There are few treatment options available for patients once they have failed standard psychopharmacological therapy for generalized anxiety disorder. Existing brain stimulation methods such as rTMS fail to target deep brain structures associated with anxiety disorders; structures such as the amygdala. In this double-blind sham-controlled clinical trial, the investigators propose to establish baseline severity of anxiety in 48 patients, then deliver eight treatments over four sessions of focused ultrasound stimulation to the amygdala. Anxiety severity will be assessed using standard psychometric scales after each session, and at follow-ups.
Recruiting
0 awards
N/A
6 criteria
Focused Ultrasound
for Bipolar Disorder
The specific aim of this proposed study is to investigate the feasibility and therapeutic potential of transcranial focused ultrasound (tFUS) as a treatment for bipolar disorder (BD). Specifically, the investigators will study the effects of amygdala tFUS on corticolimbic activation during an emotion regulation task in BD, the effects of amygdala tFUS on corticolimbic resting-state functional connectivity in BD, and explore the relationship between tFUS-associated changes in amygdala activity and mood symptoms. The investigators hypothesize that transcranial focused ultrasound (tFUS) of the amygdala will be associated with decreased amygdala activation and increased ventromedial prefrontal cortex activation during a modified version of the Multi-Source Interference Task (MSIT) paired with affective pictures from the International Affective Picture System (IAPS). The investigators also hypothesize that tFUS of the amygdala will be associated with increased resting-state functional connectivity between the amygdala and ventromedial prefrontal cortex. Finally, the investigators hypothesize that tFUS-associated reductions in amygdala activity could be positively correlated with reductions in depressive symptom scores and global improvement.
Recruiting
1 award
Phase < 1
3 criteria
More about Darin Dougherty, MD
Clinical Trial Related
4 years of experience running clinical trials · Led 7 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Darin Dougherty, MD has experience with
- Deep Brain Stimulation
- Deep Brain Stimulator
- ON/OFF Stimulation And Reward Motivation
- BrainSonix Pulsar 1002
- Low-Intensity Focused Ultrasound Of The Amygdala
- Device
Breakdown of trials Darin Dougherty, MD has run
Obsessive-Compulsive Disorder
Depression
Major Depressive Disorder
Attention Deficit Hyperactivity Disorder (ADHD)
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Darin Dougherty, MD specialize in?
Darin Dougherty, MD focuses on Obsessive-Compulsive Disorder and Depression. In particular, much of their work with Obsessive-Compulsive Disorder has involved treating patients, or patients who are undergoing treatment.
Is Darin Dougherty, MD currently recruiting for clinical trials?
Yes, Darin Dougherty, MD is currently recruiting for 2 clinical trials in Boston Massachusetts. If you're interested in participating, you should apply.
Are there any treatments that Darin Dougherty, MD has studied deeply?
Yes, Darin Dougherty, MD has studied treatments such as Deep Brain Stimulation, Deep Brain Stimulator, ON/OFF Stimulation and Reward Motivation.
What is the best way to schedule an appointment with Darin Dougherty, MD?
Apply for one of the trials that Darin Dougherty, MD is conducting.
What is the office address of Darin Dougherty, MD?
The office of Darin Dougherty, MD is located at: Massachusetts General Hospital, Boston, Massachusetts 02114 United States. This is the address for their practice at the Massachusetts General Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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