Charles Redfern | Sharp HealthCare

Dr. Charles H. Redfern

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Sharp Memorial Hospital

Studies Cancer
Studies Brain Cancer
12 reported clinical trials
43 drugs studied

Area of expertise

1

Cancer

Charles H. Redfern has run 4 trials for Cancer. Some of their research focus areas include:

Stage IV
PD-L1 positive
hCG positive
2

Brain Cancer

Charles H. Redfern has run 3 trials for Brain Cancer. Some of their research focus areas include:

Stage IV
BRAF positive
NTRK positive

Affiliated Hospitals

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Sharp Memorial Hospital

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Sharp HealthCare

Clinical Trials Charles H. Redfern is currently running

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Targeted Therapy

for Solid Tumors

This ComboMATCH patient screening trial is the gateway to a coordinated set of clinical trials to study cancer treatment directed by genetic testing. Patients with solid tumors that have spread to nearby tissue or lymph nodes (locally advanced) or have spread to other places in the body (advanced) and have progressed on at least one line of standard systemic therapy or have no standard treatment that has been shown to prolong overall survival may be candidates for these trials. Genetic tests look at the unique genetic material (genes) of patients' tumor cells. Patients with some genetic changes or abnormalities (mutations) may benefit from treatment that targets that particular genetic mutation. ComboMATCH is designed to match patients to a treatment that may work to control their tumor and may help doctors plan better treatment for patients with locally advanced or advanced solid tumors.

Recruiting

1 award

Phase 2

17 criteria

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Encorafenib/Binimetinib/Nivolumab vs Ipilimumab/Nivolumab

for Melanoma

This phase II trial compares the effect of encorafenib, binimetinib, and nivolumab versus ipilimumab and nivolumab in treating patients with BRAF- V600 mutant melanoma that has spread to the brain (brain metastases). Encorafenib and binimetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Ipilimumab and nivolumab are monoclonal antibodies that may interfere with the ability of tumor cells to grow and spread. This trial aims to find out which approach is more effective in shrinking and controlling brain metastases from melanoma.

Recruiting

1 award

Phase 2

23 criteria

More about Charles H. Redfern

Clinical Trial Related

9 years of experience running clinical trials · Led 12 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Charles H. Redfern has experience with

  • Nivolumab
  • Ipilimumab
  • Xcellerated T CellsTM
  • Pritumumab
  • LHRH Analogue
  • Abiraterone Acetate

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