Brian T. Hill, MD, PhD | Cleveland Clinic

Dr. Brian T. Hill

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Cleveland Clinic Foundation

Studies Chronic Lymphocytic Leukemia
Studies Lymphoma
9 reported clinical trials
13 drugs studied

Area of expertise

1

Chronic Lymphocytic Leukemia

Brian T. Hill has run 5 trials for Chronic Lymphocytic Leukemia. Some of their research focus areas include:

CD19 positive
CD20 positive
13q positive
2

Lymphoma

Brian T. Hill has run 5 trials for Lymphoma. Some of their research focus areas include:

CD19 positive
CD20 positive
13q positive

Affiliated Hospitals

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Cleveland Clinic Foundation

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The Cleveland Clinic Foundation

Clinical Trials Brian T. Hill is currently running

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GM T Cell Therapy Long-Term Follow-Up

for Cancer

This is a prospective study for the long-term follow-up (LTFU) of safety and efficacy for all pediatric and adult participants exposed to Gene-modified (GM) T-cell therapy participating in a previous Celgene sponsored or Celgene alliance partner sponsored study. Participants who received at least one infusion of GM T cells will be asked to enroll in this LTFU protocol upon either premature discontinuation from, or completion of the prior parent treatment protocol.

Recruiting

1 award

Phase 2 & 3

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Venetoclax + Obinutuzumab

for Leukemia

This phase III trial compares early treatment with venetoclax and obinutuzumab versus delayed treatment with venetoclax and obinutuzumab in patients with newly diagnosed high-risk chronic lymphocytic leukemia or small lymphocytic lymphoma. Venetoclax is in a class of medications called B-cell lymphoma-2 (BCL-2) inhibitors. It may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. Immunotherapy with monoclonal antibodies, such as obinutuzumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Starting treatment with the venetoclax and obinutuzumab early (before patients have symptoms) may have better outcomes for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma compared to starting treatment with the venetoclax and obinutuzumab after patients show symptoms.

Recruiting

2 awards

Phase 3

1 criteria

More about Brian T. Hill

Clinical Trial Related

7 years of experience running clinical trials · Led 9 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Brian T. Hill has experience with

  • Venetoclax
  • Obinutuzumab
  • NKX019
  • Fludarabine
  • Cyclophosphamide
  • JCAR017

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